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PROTECT-CHILD
A Privacy-Protecting Environment for Child Transplants health-related and genomic data integration in the European Reference Network.
Who are we?
PROTECT-CHILD is a multidisciplinary consortium funded by the European Union, bringing together specialists in paediatric transplantation, genetics, computer engineering, information security, and legal and ethical experts. Our collaboration integrates clinical and genetic research with the development of secure data analysis platforms to improve the care of transplanted children across Europe.
What is our objective?
The main objective is to personalise treatments for transplanted children by identifying genetic and epigenetic biomarkers. This will enable tailored immunosuppressive therapies while reducing the risk of organ rejection, infections and other adverse reactions.
The University of Granada, through the Youngner Chair in Empirical Bioethics (CYBE), leads WP11, ensuring compliance with ethical standards in the management and use of children’s health data for research and improved post-transplant care.
What does the project involve?
PROTECT-CHILD develops an innovative infrastructure integrating clinical and genomic data from transplanted children, ensuring privacy and data security to support personalised medicine and optimise clinical outcomes.
How do we do it?
Within an observational medicinal study involving 200 paediatric liver and kidney transplant recipients, a secure platform will integrate clinical and genomic data from European hospitals. Using genetic sequencing, privacy-preserving data integration and artificial intelligence, predictive biomarkers will be identified to personalise treatment.
Impact
PROTECT-CHILD will lay the foundations for personalised paediatric transplantation, increasing survival and improving patients’ quality of life. The project will contribute to safer, more effective and individually tailored healthcare.
Funding
Granting authority: European Health and Digital Executive Agency (HaDEA).
Programme: Horizon Europe.
Funded by the European Union: HORIZON-HLTH-2023-TOOL-05-04: Better integration and use of health-related real-world and research data, including genomics, for improved clinical outcomes.
This project has received funding from the European Union’s Horizon Europe research and innovation programme under Grant Agreement No. 101137423.
